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SKLB-610是一种多靶点的酪氨酸激酶 (tyrosine kinases)抑制剂。它对VEGFR2的抑制作用最为有效,是FGFR2和PDGFR的弱抑制剂。
中文别名:
N-甲基-4-[4-[3-(三氟甲基)苯甲酰胺基]苯氧基]-2-吡啶甲酰胺
[1]. Cao ZX, et al. SKLB610: a novel potential inhibitor of vascular endothelial growth factor receptor tyrosine kinases inhibits angiogenesis and tumor growth in vivo. Cell Physiol Biochem. 2011;27(5):565-74.
[2]. Luo X, et al. Pharmacokinetic studies of a novel multikinase inhibitor for treating cancer by HPLC-UV. J Chromatogr Sci. 2013 Jan;51(1):17-20.
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