0576-88813233
A66 是一种高特异性的选择性的 p110α 抑制剂,IC50 为 32 nM。
中文别名:
(2S)-N1-(2-叔丁基-4'-甲基[4,5'-联噻唑]-2'-基)-1,2-吡咯烷二甲酰胺;
A66, 98%, a potent and specific p110α inhibitor;
A66, 一种高活性的P110Α特异性抑制剂;
A66,P110Α抑制剂
物化属性:
密度:1.354
[1]. Jamieson S, et al. A drug targeting only p110α can block phosphoinositide 3-kinase signalling and tumour growth in certain cell types. Biochem J, 2011, 438(1), 53-62.
[2]. Sun M, et al. Cancer-derived mutations in the regulatory subunit p85alpha of phosphoinositide 3-kinase function through the catalytic subunit p110alpha. Proc Natl Acad Sci U S A, 2010, 107(35), 15547-15552.
版权所有 Copyright(C) 2018-2024 台州市科瑞生物技术有限公司