0576-88813233
ELR510444是新型微管阻断剂,抑制MDA-MB-231细胞增殖的IC50值为30.9nM,非P-gp底物分子。
英文别名:
KB-76777; EX-A653; BC600666; AK204430
产品名称:
N-[5-(5-氰基-2-噻吩基)-2-甲基苯基]-4-甲基苯磺酰胺
[1]. Risinger AL, et al. ELR510444, a novel microtubule disruptor with multiple mechanisms of action. J Pharmacol Exp Ther. 2011 Mar;336(3):652-60.
[2]. Carew JS, et al. ELR510444 inhibits tumor growth and angiogenesis by abrogating HIF activity and disrupting microtubules in renal cell carcinoma. PLoS One. 2012;7(1):e31120.
版权所有 Copyright(C) 2018-2022 台州市科瑞生物技术有限公司