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Tenapanor HCl

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产品信息

产品名称：Tenapanor HCl	纯度：99% min
CAS NO：1234365-97-9	溶解度：Soluble in DMSO and water
分子式：C₅₀H₆₈Cl₆N₈O₁₀S₂	包装：可按客户要求包装
分子量：1217.97	贮存：-20℃

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备注说明

Tenapanor, also known as AZD-1722 and RDX 5791, is an inhibitor of the sodium-proton (Na(+)/H(+)) exchanger NHE3, which plays a prominent role in sodium handling in the gastrointestinal tract and kidney. Tenapanor possesses an excellent preclinical safety profile and, as of now, there are no serious concerns about its side effects.

参考文献

[1]. Spencer AG, et al. Intestinal inhibition of the Na+/H+ exchanger 3 prevents cardiorenal damage in rats and inhibitsNa+ uptake in humans.