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CYM2503

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产品信息

产品名称：CYM2503	纯度：98% min
CAS NO：1308833-36-4	溶解度：
分子式：C₄₅H₅₅N₅O₇	包装：可按客户要求包装
分子量：777.947	贮存：-20℃

质量控制

备注说明

CYM2503 is a positive allosteric modulator (PAM) of the GAL2 receptor which potentiates galanin-induced IP1 production in vitro. The compound has no affinity for the orthosteric galanin binding site of the receptor (as measured by its inability to displace iodinated galanin, or to induce IP1 accumulation on its own).

参考文献

1: Lu X, Roberts E, Xia F, Sanchez-Alavez M, Liu T, Baldwin R, Wu S, Chang J, Wasterlain CG, Bartfai T. GalR2-positive allosteric modulator exhibits anticonvulsant effects in animal models. Proc Natl Acad Sci U S A. 2010 Aug 24;107(34):15229-34. doi: 10.1073/pnas.1008986107. PubMed PMID: 20660766; PubMed Central PMCID: PMC2930524.