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来沙骨化醇 Lexacalcitol (KH1060) 是一种维生素 D 类似物,是细胞生长和免疫反应的有效调节剂。Lexacalcitol 可用于移植排斥反应、银屑病、癌症和自身免疫性疾病的研究。
物化性质:
密度:1.07g/cm3
沸点:600.3ºC at 760mmHg
闪点:316.8ºC
折射率:1.541
蒸汽压:6.49E-17mmHg at 25°C
[1]. L Binderup, et al. 20-epi-vitamin D3 analogues: a novel class of potent regulators of cell growth and immune responses. Biochem Pharmacol. 1991 Sep 27;42(8):1569-75.
[2]. C Gysemans, et al. A combination of KH1060, a vitamin D(3) analogue, and cyclosporin prevents early graft failure and prolongs graft survival of xenogeneic islets in nonobese diabetic mice. Transplant Proc. 2001 May;33(3):2365.
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