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西奥骨化醇 Seocalcitol 是一种 vitamin D 类似物,作用于人骨肉瘤 MG-63 细胞,结合 vitamin D 受体蛋白,Kd 为 0.27 nM。
物化性质:
密度:1.06g/cm3
沸点:608.5ºC at 760mmHg
闪点:252.3ºC
折射率:1.56
蒸汽压:2.4E-17mmHg at 25°C
[1]. Wiberg K, et al. Studies on two new vitamin D analogs, EB 1089 and KH 1060: effects on bone resorption and osteoclast recruitment in vitro. Bone. 1995 Oct;17(4):391-5.
[2]. Roy S, et al. Comparative effects of 1,25-dihydroxyvitamin D3 and EB 1089 on mouse renal and intestinal 25-hydroxyvitamin D3-24-hydroxylase. J Bone Miner Res. 1995 Dec;10(12):1951-9
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