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Pimecrolimus是免疫亲和素(immunophilin)配体,能特异地与胞质受体(immunophilin macrophilin-12)相结合。
物化性质: 外观与性状:白色结晶粉末 密度:1.19 沸点: 866.1ºC at 760 mmHg 闪点:477.6ºC 折射率:1.543
[1]. Nghiem, P., G. Pearson, and R.G. Langley, Tacrolimus and pimecrolimus: from clever prokaryotes to inhibiting calcineurin and treating atopic dermatitis. J Am Acad Dermatol, 2002. 46(2): p. 228-41.
[2]. Gupta, A.K. and M. Chow, Pimecrolimus: a review. J Eur Acad Dermatol Venereol, 2003. 17(5): p. 493-503.
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