DM1-SMe is a potent maytansinoid microtubular inhibitor and an unconjugated DM1 as a mixed disulfide with thiomethane to cap its sulfhydryl group. DM1-SMe can be readily conjugate to the SH group of an antibody to form antibody-drug conjugate (ADC).
中文别名:
N2'-去乙酰基-N2'-[3-(甲基二硫基)-1-氧代丙基]美登素; 美登素衍生物
物化属性:
PSA:207.07000
LOGP:5.30960