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GJ103 游离

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产品信息

产品名称：GJ103 游离	纯度：99% min
CAS NO：1459687-89-8	溶解度：
分子式：C₁₆H₁₄N₄O₃S	包装：可按客户要求包装
分子量：342.372	贮存：-20℃

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备注说明

GJ-103 is an active analog of the read-through compound GJ072. Chemical-induced read through of premature stop codons might be exploited as a potential treatment strategy for genetic disorders caused by nonsense mutations.

参考文献

1: Du L, Jung ME, Damoiseaux R, Completo G, Fike F, Ku JM, Nahas S, Piao C, Hu H,
Gatti RA. A new series of small molecular weight compounds induce read through of
all three types of nonsense mutations in the ATM gene. Mol Ther. 2013
Sep;21(9):1653-60. doi: 10.1038/mt.2013.150. Epub 2013 Jun 18. PubMed PMID:
23774824; PubMed Central PMCID: PMC3776636.