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去氨加压素 Desmopressin

去氨加压素 Desmopressin 16679-58-6
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产品信息
产品名称:去氨加压素 Desmopressin 纯度:98% min
CAS NO:16679-58-6 溶解度:
分子式:C46H64N14O12S2 包装:可按客户要求包装
分子量:1069.22 贮存:-20℃
质量控制
备注说明

Desmopressin is a synthetic analog of the pituitary hormone, ARGININE VASOPRESSIN. Its action is mediated by the VASOPRESSIN receptor V2. It has prolonged antidiuretic activity, but little pressor effects. It also modulates levels of circulating FACTOR VIII and VON WILLEBRAND FACTOR. It is a medication used to treat diabetes insipidus, bedwetting, hemophilia A, von Willebrand disease, and high blood urea levels. In hemophilia A and von Willebrand disease, it should only be used for mild to moderate cases. It may be given in the nose, by injection into a vein, by mouth, or under the tongue.

参考文献

1: Weiss JP, van der Meulen EA, Juul KV. Low-dose Desmopressin Orally Disintegrating Tablet: Suggested Clinically Meaningful Benefit in Patients with Nocturia Due to Nocturnal Polyuria. Eur Urol Focus. 2018 Nov 20. pii: S2405-4569(18)30333-X. doi: 10.1016/j.euf.2018.11.001. [Epub ahead of print] PubMed PMID: 30470646.

2: Singh K, Kanodia AK, Ross P, Torgersen A, Maclean J, Leese G, Hossain-Ibrahim K. Xanthomatous hypophysitis causing hypogonadotropic hypogonadism resulting in delayed presentation of slipped capital femoral epiphysis. Br J Neurosurg. 2018 Nov 19:1-4. doi: 10.1080/02688697.2018.1525482. [Epub ahead of print] PubMed PMID: 30450996.

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