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唑喹达三盐酸盐Zosuquidar trihydrochloride是P-糖蛋白的抑制剂, Ki值为59 nM。
物化属性:
熔点:172-176°C
沸点:690.5°Cat760mmHg
闪光点:371.4°C
PSA:48.83000
LOGP:7.49320
[1]. Cripe LD, et al. Zosuquidar, a novel modulator of P-glycoprotein, does not improve the outcome of older patients with newly diagnosed acute myeloid leukemia: a randomized, placebo-controlled trial of the Eastern Cooperative Oncology Group 3999. Blood. 201
[2]. Tang R, et al. Zosuquidar restores drug sensitivity in P-glycoprotein expressing acute myeloid leukemia (AmL). BMC Cancer. 2008 Feb 13;8:51.
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