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盐酸莫西沙星Moxifloxacin HCl

盐酸莫西沙星Moxifloxacin HCl 186826-86-8
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产品信息
产品名称:盐酸莫西沙星Moxifloxacin HCl 纯度:99%min
CAS NO:186826-86-8 溶解度:Soluble in DMSO
分子式:C21H24FN3O4.HCl 包装:可按客户要求包装。
分子量:437.89 贮存:Store at -20℃ 3 years
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备注说明

盐酸莫西沙星Moxifloxacin HCl是氟喹诺酮类抗生素。Moxifloxacin (Hydrochloride) is a synthetic fluoroquinolone antibiotic agent. Target: Antibacterial Moxifloxacin is an extended-spectrum fluoroquinolone which has improved coverage against gram-positive cocci and atypical pathogens compared with older fluoroquinolone agents, while retaining good activity against gram-negative bacteria. The antibacterial spectrum of moxifloxacin includes all major upper and lower respiratory tract pathogens; it is one of the most active fluoroquinolones against pneumococci, including penicillin- and macrolide-resistant strains [1]. Moxifloxacin has limited phototoxic potential. In clinical trials, moxifloxacin had clinical success rates of 88-97% and bacteriologic eradication rates of 90-97%. Moxifloxacin is a safe and effective antimicrobial that will be useful for treating acute sinusitis, acute bacterial exacerbations of chronic bronchitis, and community-acquired pneumonia [2]. Moxifloxacin possibly stimulates lipid peroxidation and enhances phagocytosis, as depicted by MDA production and survival prolongation, without being toxic as depicted by white blood cell count [3]. Clinical indications: Abdominal abscess; Acute bronchitis; Acute sinusitis; Bacterial infection Toxicity: Symptoms of overdose include CNS and gastrointestinal effects such as decreased activity, somnolence, tremor, convulsions, vomiting, and diarrhea. The minimal lethal intravenous dose in mice and rats is 100 mg/kg.

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