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普那霉素 Pristinamycin

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产品信息

产品名称：普那霉素 Pristinamycin	纯度：98% min
CAS NO：270076-60-3	溶解度：Soluble in DMSO
分子式：C₄₅H₅₄N₈O₁₀	包装：可按客户要求包装。
分子量：1349.506	贮存：-20℃

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备注说明

Pristinamycin, also known as Virginiamycin antibiotic complex; NSC-246121; Antibiotic 899; Founderguard, is an antibiotic used primarily in the treatment of staphylococcal infections, and to a lesser extent streptococcal infections. Pristinamycin is a mixture of two components that have a synergistic antibacterial action. Pristinamycin IA is a macrolide, and results in pristinamycin's having a similar spectrum of action to erythromycin. Virginiamycin complex contains two streptogramin antibiotics, virginiamycin M1 (75%) and virginiamycin S1 (25%).

参考文献

1: Mast Y, Guezguez J, Handel F, Schinko E. A Complex Signaling Cascade Governs Pristinamycin Biosynthesis in Streptomyces pristinaespiralis. Appl Environ Microbiol. 2015 Oct;81(19):6621-36. doi: 10.1128/AEM.00728-15. Epub 2015 Jul 17. PubMed PMID: 26187956; PubMed Central PMCID: PMC4561715.

2: Cooper EC, Curtis N, Cranswick N, Gwee A. Pristinamycin: old drug, new tricks? J Antimicrob Chemother. 2014 Sep;69(9):2319-25. doi: 10.1093/jac/dku167. Epub 2014 Jun 2. Review. PubMed PMID: 24891428.