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ML311

ML311 315698-17-0
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产品信息
产品名称:ML311 纯度:98% min
CAS NO:315698-17-0 溶解度:
分子式:C23H24F3N3O 包装:可按客户要求包装
分子量:415.45 贮存:-20 ℃
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备注说明

ML311, also known as EU-5346, is a potent and selective inhibitor of the Protein-Protein Interaction of Mcl-1 and Bim. ML311 Potently and Selectively Disrupts the Protein-Protein Interaction of Mcl-1 and Bim. EU-5346 will be a useful tool for studying lymphoid tumorigenesis and to demonstrate the potential for using this strategy in therapies intended to bypass apoptosis resistance pathways that are activated in drug-resistant tumors.

参考文献
[1]. Bannister T, et al. ML311: A Small Molecule that Potently and Selectively Disrupts the Protein-Protein Interaction of Mcl-1 and Bim: A Probe for Studying Lymphoid Tumorigenesis. Biotechnology Information (US); 2010-2012 Apr 16.

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