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环孢菌素 C

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产品信息

产品名称：环孢菌素 C	纯度：98% min
CAS NO：59787-61-0	溶解度：Soluble in DMSO
分子式：C₆₂H₁₁₁N₁₁O₁₃	包装：可按客户要求包装
分子量：1218.610	贮存：-20℃

质量控制

备注说明

Cyclosporin C is a broad-spectrum antifungal agent against filamentous phytopathogenic fungi but no activity against bacteria or yeasts.

物化属性:

外观与形状：无色至灰白色结晶固体

密度：1.033

熔点：152-155 ºC

沸点：1316 °C at 760 mmHg

折射率：1.472

闪光点：749.7 °C

PSA：299.03000

LOGP：3.12030

参考文献

1: Xu L, Li Y, Biggins JB, Bowman BR, Verdine GL, Gloer JB, Alspaugh JA, Bills GF. Identification of cyclosporin C from Amphichorda felina using a Cryptococcus neoformans differential temperature sensitivity assay. Appl Microbiol Biotechnol. 2018 Mar;102(5):2337-2350. doi: 10.1007/s00253-018-8792-0. Epub 2018 Feb 2. PubMed PMID: 29396588.

2: Iijima K, Sako M, Oba MS, Ito S, Hataya H, Tanaka R, Ohwada Y, Kamei K, Ishikura K, Yata N, Nozu K, Honda M, Nakamura H, Nagata M, Ohashi Y, Nakanishi K, Yoshikawa N; Japanese Study Group of Kidney Disease in Children. Cyclosporine C2 monitoring for the treatment of frequently relapsing nephrotic syndrome in children: a multicenter randomized phase II trial. Clin J Am Soc Nephrol. 2014 Feb;9(2):271-8. doi: 10.2215/CJN.13071212. Epub 2013 Nov 21. PubMed PMID: 24262503; PubMed Central PMCID: PMC3913253.