Benzamidine is a reversible competitive inhibitor of trypsin, trypsin-like enzymes and serine proteases.
It is often used as a ligand in protein crystallography to prevent proteases from degrading a protein of interest; the triangular diamine group at the bottom gives it a very obvious 'stick-man' shape which shows up in difference density maps. The benzamidine moiety is also found in some pharmaceuticals, like dabigatran.
物化性质:
密度:1.09 g/cm3
沸点:208.5ºC at 760 mmHg
熔点:65-70ºC
闪点:79.9ºC