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GBR 12935 dihydrochloride 是多巴胺再吸收抑制剂。
物化属性:
密度:1.067
沸点:564ºC at 760 mmHg
折射率:1.576
闪光点:294.9ºC
颜色:white
PSA:90.31000
LOGP:6.52280
[1]. Hiroi T, et al. Specific binding of 1-[2-(diphenylmethoxy)ethyl]-4-(3-phenyl propyl) piperazine (GBR-12935), an inhibitor of the dopamine transporter, to human CYP2D6. Biochem Pharmacol. 1997 Jun 15;53(12):1937-9.
[2]. Rahman S, et al. Negative interaction of dopamine D2 receptor antagonists and GBR 12909 and GBR 12935 dopamine uptake inhibitors in the nucleus accumbens. Eur J Pharmacol. 2001 Feb 23;414(1):37-44.
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