0576-88813233
Ponesimod(ACT-128800)是S1P1受体选择性口服型激动剂。
物化属性:
PSA:107.66000
LOGP:4.33230
[1]. Piali L, et al. The selective sphingosine 1-phosphate receptor 1 agonist ponesimod protects against lymphocyte-mediated tissue inflammation. J Pharmacol Exp Ther. 2011 May;337(2):547-56.
[2]. Bolli MH, et al. 2-imino-thiazolidin-4-one derivatives as potent, orally active S1P1 receptor agonists. J Med Chem. 2010 May 27;53(10):4198-211.
版权所有 Copyright(C) 2018-2024 台州市科瑞生物技术有限公司