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布喹那Brequinar (DUP785) 是一种有效的 dihydroorotate dehydrogenase 抑制剂,同时为广谱的抗病毒剂。
物化属性:
密度:1.319
沸点:550.9°Cat760mmHg
折射率:1.644
闪光点:287°C
[1]. Schnellrath LC, et al. Potent antiviral activity of brequinar against the emerging Cantagalo virus in cell culture. Int J Antimicrob Agents. 2011 Nov;38(5):435-41.
[2]. Qing M, et al. Characterization of dengue virus resistance to brequinar in cell culture. Antimicrob Agents Chemother. 2010 Sep;54(9):3686-95.
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